TZIELD® Infusion Therapy

About TZIELD® Therapy

TZIELD® (teplizumab-mzwv) is a groundbreaking prescription medication that represents a significant milestone in diabetes care. TZIELD® is a CD3-directed monoclonal antibody that works by targeting a temporarily modifying the immune system's T-cells, which are responsible for attacking and destryoing insulin-producing beta cells in the pancrease.

Condition treated by this therapy

TZIELD® is FDA-approved specifically to delay the onset of stage 3 (insulin-dependent) type 1 diabetes in adults and children 8 years of age and older who have stage 2 type 1 diabetes.

TZIELD® Price

The out-of-pocket ILUMYA® price will vary depending on your insurance coverage. If you have questions about your coverage, contact your insurance provider.

No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities, contact a member of our Violet Health team.

What to Expect During TZIELD® Infusion Therapy

Once your healthcare provider conducts tests to confirm stage 2 type 1 diabetes, you'll book your appointment at Violet Health. Before treatment, you'll likely recieve premedication with antipyretics (fever reducers), antihistamines, and/or antiemetics (anti-nausea medications) to help prevent or reduce potential side effects. You'll receive TZIELD® as an intravenous infusion over a minimum of 30 minutes once daily for a 14-day consecutive treatment course.

TZIELD® Side Effects

The most common side effects of TZIELD® include:

Cytokine Release Syndrome (CRS): This is one of the most significant potential side effects and typically occurs during the first 5 days of treatment. Symptoms may includes:
- Fever
- Fatigue
- Headache
- Muiscle and joint pain
- Increased liver enzymes
- Nausea
Decreased white blood cell counts: Lymphopenia (low lymphocyte count). These conditions typically resolve within two weeks after treatment completion without specific intervention.
Skin rash
Headache
Injection-site reactions

TZIELD® Therapy at Violet Health

Your comfort during TZIELD® therapy at Violet Health is our priority. Our TZIELD® patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Plus, Violet Health’s evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.

Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.

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Helpful Resources

Patient Forms

Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!