VYVGART HYTRULO® Infusion Therapy

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About VYVGART® Infusion Therapy

VYVGART HYTRULO® is a subcutaneous (subQ) version of VYVGART®, which means it is administered under the skin as opposed to in a vein. VYVGART HYTRULO® contains the same active ingredient as VYVGART® but is formulated with hyalurondinase to allow for subQ injection.

The medication works works by blocking the FcRn receptor, which normally recycles immunoglobin (IgG) antibodies in the body. By preventing this recycling process, VYVGART® reduces circulating levels of pathogenic IgG antibodies that attack acetylcholine receptors in myasthenia gravis patients.

Condition treated by this therapy

VYVGART HYTRULO® is an FDA approved biologic therapy indicated to treat Generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive.

VYVGART HYTRULO is also approved for the treatment of adult patients with chronic inflammatory demyelinating polyneuropathy (CIDP).

VYVGART® Price

The cost of prescription medications can vary depending on your insurance coverage. If you're concerned about the price of your medication:

Contact your insurance provider to understand your coverage
Ask your doctor or pharmacist about lower-cost alternatives
Check with the drug manufacturer about financial assistance programs
Explore patient assistance options if you're uninsured or underinsured

Remember, many resources exist to help patients access necessary medications. Don't hesitate to ask for help if you're struggling with medication costs. No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities, contact a member of our Violet Health team.

What to Expect During VYVGART HYTRULO® Infusion Therapy

Please arrive to your appointment early and well hydrated.

Frequency: Once weekly injections for 4 consecutive weeks (one treatment cycle)
Administration: Subcutaneous injection, typically in the abdominal area (avoiding the navel area)
Duration: Each injection takes approximately 20-30 seconds

Regular assessments to evaludate treatment response and managing side effects are typical follow-up procedures. Some patients may begin to see improvement in symptoms within the first few weeks of treatment. The effects of one treatment cycle may last several months, and additional cycles can be administered based on clinical response and physician assessment.

VVYVGART HYTRULO® Side Effects

Prior to recieving any injection therapies, please inform our clinic of any known allergies to medications. Side effects of VYVGART HYTRULO® may include:

Injection site reactions
headache (including migraine)
paresthesias (feelings of numbness or pins and needles)
muscle pain.
respiratory tract infection*
urinary tract infection (UTI)*

These are not all possible side effects. More serious reactions can occure. If you experience a rash or hives, swelling of your face, lips or throat, experience difficulty breathing, chest pain or rapid heartbeat please alert staff promptly.

Other serious side effects can include fever, chills, persistent cough, sore throat, urinary tract infection symptoms or unusual fatigue. VYVGART HYTRULO® may lower the ability to fight infections due to reduced IgG levels.

VVYVGART HYTRULO® Infusion Therapy at Violet Health

Your comfort during VYVGART HYTRULO® infusion therapy at Violet Health is our priority. Our patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Plus, Violet Health’s evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.

Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.

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Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!